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2013-2017 MEXT KAKENHI Grant-in-Aid for Specially Promoted Research

Measurement of Biological Locomotion Using MEMS Multi-Axis Force Sensors




Objective

Adhesion and spreading on scaffolding materials is essential for most mammalian cells to function properly. It is also known that adhered cells recognize the stiffness of the scaffold by generating force against the scaffold and adjust its function according to the stiffness. The aim of our group is to reveal the mechanical characteristic of cells by measuring the force generated by cells against the scaffolds.

Subjects
1.Measurement of force caused by locomotion of a cell

1-1.Measurement of force caused by locomotion of cell by probe type sensor
Researches Now constructing

　　　

1-2.Measurement of force caused by locomotion of cell by force sensor with micro pillar
Researches Now constructing

2.Measurement of a force caused by a movement of a small liquid droplet

2-1.Measurement of a force caused by a droplet sliding

Researches Now Constructing。

　　　

2-2.Measurement of a viscosity of a droplet according to its vibrating frequency
Researches Now Constructing。

東京大学大学院　情報理工学系研究科　知能機械情報学専攻　下山研究室
東京都文京区本郷7-3-1 工学部2号館8階81B
TEL:03-5841-0461 Fax:03-3818-0835
Shimoyama Lab., Department of Mechano-Informatics, Graduate School of Information Science and Technology, The University of Tokyo.
7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.